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The NHS has put out a warning about this on its website. The statement reads: "Do not take omeprazole for longer than two weeks if you bought it without a prescription. See a GP if your symptoms get worse or do not get better."
One risk linked to long-term use of PPIs is a heightened risk of a bacterial infection known as Clostridioides difficile. This type of bacterium can lead to an infection in the intestines, resulting in diarrhoea and additional symptoms such as abdominal pain and fever.
This bacterium usually causes illness when antibiotics disturb the balance of normal gut bacteria, enabling Clostridioides difficile to grow and generate toxins. Symptoms include:
